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Article

FOXA2 Cooperates with Mutant KRAS to Drive Invasive Mucinous Adenocarcinoma of the Lung.

Cancer research - 2 May 2023

Tomoshige Koichi, Stuart William D, Fink-Baldauf Iris M, Ito Masaoki, Tsuchiya Tomoshi, Nagayasu Takeshi, Yamatsuji Tomoki, Okada Morihito, Fukazawa Takuya, Guo Minzhe, Maeda Yutaka

Abstract excerpt

The endoderm-lineage transcription factor FOXA2 has been shown to inhibit lung tumorigenesis in in vitro and xenograft studies using lung cancer cell lines. However, FOXA2 expression in primary lung tumors does not correlate with an improved patient survival rate, and the functional role of FOXA2 in primary lung tumors remains elusive. To understand the role of FOXA2 in primary lung tumors in vivo, here, we...

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Share to Adenocarcinoma, Mucinous
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37067057
DOI: 10.1158/0008-5472.CAN-22-2805
PMCID: PMC10160002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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