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Article

Druggable oncogene fusions in invasive mucinous lung adenocarcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jun 2014

Nakaoku Takashi, Tsuta Koji, Ichikawa Hitoshi, Shiraishi Kouya, Sakamoto Hiromi, Enari Masato, Furuta Koh, Shimada Yoko, Ogiwara Hideaki, Watanabe Shun-ichi, Nokihara Hiroshi, Yasuda Kazuki, Hiramoto Masaki, Nammo Takao, Ishigame Teruhide, Schetter Aaron J, Okayama Hirokazu, Harris Curtis C, Kim Young Hak, Mishima Michiaki, Yokota Jun, Yoshida Teruhiko, Kohno Takashi

Abstract excerpt

PURPOSE: To identify druggable oncogenic fusions in invasive mucinous adenocarcinoma (IMA) of the lung, a malignant type of lung adenocarcinoma in which KRAS mutations frequently occur. EXPERIMENTAL DESIGN: From an IMA cohort of 90 cases, consisting of 56 cases (62%) with KRAS mutations and 34 cases without (38%), we conducted whole-transcriptome sequencing of 32 IMAs, including 27 cases without KRAS mutations....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24727320
DOI: 10.1158/1078-0432.CCR-14-0107
PMCID: PMC6329293

Genes

KRAS
NRG1
BRAF
ERBB4
EZR
TRIM24
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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