Article
KRAS and NKX2-1 Mutations in Invasive Mucinous Adenocarcinoma of the Lung.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Apr 2016
Hwang David H, Sholl Lynette M, Rojas-Rudilla Vanesa, Hall Dimity L, Shivdasani Priyanka, Garcia Elizabeth P, MacConaill Laura E, Vivero Marina, Hornick Jason L, Kuo Frank C, Lindeman Neal I, Dong Fei
Abstract excerpt
INTRODUCTION: Mucinous differentiation is observed in a subset of lung adenocarcinomas with unique clinical and pathological features, but the biology of these neoplasms is poorly understood. METHODS: We apply targeted next-generation sequencing to characterize the mutational profiles of 21 invasive mucinous adenocarcinomas, mixed mucinous/nonmucinous adenocarcinomas, and adenocarcinomas with mucinous features of...
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