Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Review of the Biosynthesis and Structural Implications of Insulin Gene Mutations Linked to Human Disease.

Cells - 25 Mar 2023

Ataie-Ashtiani Sara, Forbes Briony

Abstract excerpt

The discovery of the insulin hormone over 100 years ago, and its subsequent therapeutic application, marked a key landmark in the history of medicine and medical research. The many roles insulin plays in cell metabolism and growth have been revealed by extensive investigations into the structure and function of insulin, the insulin tyrosine kinase receptor (IR), as well as the signalling cascades, which occur...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diet, Metabolism, and Disease
Share to Insulin
Share to Insulin-Secreting Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Metabolism, Diabetes, and Cancer

Share to Mutation

Share to Pancreatic function and diabetes

Share to Proinsulin

Share to Protein Transport

Source

Open in PubMed Open full text

Identifiers

PMID: 37048081
DOI: 10.3390/cells12071008
PMCID: PMC10093311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Review of the Biosynthesis and Structural Implications of Insulin Gene Mutations Linked to Human Disease.PMID 37048081Read ↗

Lessons learned from molecular biology of insulin-gene mutations.Semantic proximity Read ↗

[Classification of mutations in the insulin receptor gene].Semantic proximity Read ↗

In celebration of a century with insulin - Update of insulin gene mutations in diabetes.Semantic proximity Read ↗

Molecular biology of insulin resistance.Semantic proximity Read ↗

[Insulin gene mutations].Semantic proximity Read ↗

INS-gene mutations: from genetics and beta cell biology to clinical disease.Semantic proximity Read ↗

Insulin gene mutations and posttranslational and translocation defects: associations with diabetes.Semantic proximity Read ↗

Comprehensive Computational Analysis Revealed Seven Novel Mutations in Human Insulin geneSemantic proximity Read ↗

Molecular defects of the insulin receptor gene.Semantic proximity Read ↗

GENETICS IN ENDOCRINOLOGY: Genetic forms of severe insulin resistance: what endocrinologists should knowSemantic proximity Read ↗

Mechanisms of hormone resistance: lessons from insulin-resistant patients.Semantic proximity Read ↗

Insulin resistance due to mutations of the insulin receptor gene: an overview.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.