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Article

Mechanisms of hormone resistance: lessons from insulin-resistant patients.

Acta paediatrica (Oslo, Norway : 1992). Supplement - 1 Apr 1994

Taylor S I, Accili D, Haft C R, Hone J, Imai Y, Levy-Toledano R, Quon M J, Suzuki Y, Wertheimer E

Abstract excerpt

Hormones are secreted by endocrine glands and transported to the target cell at which the hormone acts. The hormone binds to its receptor, thereby eliciting various biological responses within the target cell. Examples of disease mechanisms that function at the different stages in the development of the insulin receptor, and result in insulin resistance, are discussed in this review. Antibodies to insulin can...

Topics

Genetic Diseases, Inborn
Hormones
Humans
Insulin
Insulin Resistance
Mutation
Receptor, Insulin

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7949626
DOI: 10.1111/j.1651-2227.1994.tb13300.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7949626-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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