Article
Lessons learned from molecular biology of insulin-gene mutations.
Diabetes care - 1 Jun 1990
Steiner D F, Tager H S, Chan S J, Nanjo K, Sanke T, Rubenstein A H
Abstract excerpt
Studies on naturally occurring and man-made mutations in the insulin gene have provided new insights into insulin biosynthesis, action, and metabolism. Ten families have been identified in which one or more members have single-point mutations in their insulin genes that result in amino acid subst...
Topics
- Animals
- Genes
- Humans
- Insulin
- Molecular Biology
- Mutation
- Proinsulin
- Protein Precursors