Article

Targeted Hybridization Capture of SARS-CoV-2 and Metagenomics Enables Genetic Variant Discovery and Nasal Microbiome Insights

2021-03-20

Abstract excerpt

<h4>ABSTRACT</h4> The emergence of novel SARS-CoV-2 genetic variants that may alter viral fitness highlights the urgency of widespread next-generation sequencing (NGS) surveillance. To profile genetic variants, we developed and clinically validated a hybridization capture SARS-CoV-2 NGS assay, integrating novel methods for panel design using dsDNA biotin-labeled probes, and built accompanying software. The positiv...

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Literature Corpus work: 9bdca6c2-dd5b-5d84-8c48-2f19ded69955
DOI: 10.1101/2021.03.16.21252988

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