Article
Protocol for a nested case-control study design for omics investigations in the Environmental Determinants of Islet Autoimmunity cohort.
Annals of medicine - 1 Dec 2023
Oakey Helena, Giles Lynne C, Thomson Rebecca L, Lê Cao Kim-Anh, Ashwood Pat, Brown James D, Knight Emma J, Barry Simon C, Craig Maria E, Colman Peter G, Davis Elizabeth A, Hamilton-Williams Emma E, Harrison Leonard C, Haynes Aveni, Kim Ki Wook, Mallitt Kylie-Ann, McGorm Kelly, Morahan Grant, Rawlinson William D, Sinnott Richard O, Soldatos Georgia, Wentworth John M, Couper Jennifer J, Penno Megan A S
Abstract excerpt
Background: The Environmental Determinants of Islet Autoimmunity (ENDIA) pregnancy-birth cohort investigates the developmental origins of type 1 diabetes (T1D), with recruitment between 2013 and 2019. ENDIA is the first study in the world with comprehensive data and biospecimen collection during pregnancy, at birth and through childhood from at-risk children who have a first-degree relative with T1D....
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