Long-Term Follow-Up Incidence of Type 1 Diabetes and Associated Autoimmune Diseases in First-Degree Relatives.

doi:10.1111/dom.71194

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Article

Long-Term Follow-Up Incidence of Type 1 Diabetes and Associated Autoimmune Diseases in First-Degree Relatives.

Diabetes, obesity & metabolism - 1 Oct 2026

Christensen Julie H, Petersen Gitte Lindved, Kaur Simranjeet, Lind Alexander, Hamdan Samia, Scherman Maria Naredi, Johannesen Jesper, Agardh Daniel, Antvorskov Julie C, Pociot Flemming

Abstract excerpt

BACKGROUND: First-degree relatives (FDRs) of individuals with type 1 diabetes (T1D) carry a significantly elevated risk of developing autoimmune diseases, including celiac disease (CD) and autoimmune thyroid disease (AITD). The DiaUnion 1.0 study aimed to characterize one-time autoantibodies, genetic risk profiles and long-term progression to T1D, CD or AITD in siblings of children newly diagnosed with T1D....

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Topics

Humans
Diabetes Mellitus, Type 1
Female
Male
Incidence
Follow-Up Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Autoantibodies

Child

Adolescent

Denmark

Genetic Predisposition to Disease

Autoimmune Diseases

Thyroiditis, Autoimmune

Celiac Disease

Child, Preschool

Siblings

Adult

Genetic Risk Score

Source

Open in PubMed Open full text

Identifiers

PMID: 42563371
DOI: 10.1111/dom.71194
PMCID: PMC13538825

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