Article
A Secular Increase in the Incidence of Islet Autoimmunity Among Colorado Children With Moderate-Risk HLA Genotypes.
Diabetes care - 1 Sept 2026
Hohsfield Kirk R, Dong Fran, Waugh Kathleen, Steck Andrea K, Buckner Teresa, Johnson Randi K, Carry Patrick M, Frohnert Brigitte, Rewers Marian, Norris Jill M
Abstract excerpt
OBJECTIVE: We investigated islet autoimmunity (IA) incidence trends among Colorado children born 1993-2010 in Diabetes Autoimmunity Study in the Young (DAISY) and The Environmental Determinants of Diabetes in the Young (TEDDY) and whether HLA genotype or early-life environmental exposures contributed to observed increases. RESEARCH DESIGN AND METHODS: We analyzed the risk of IA among 2,734 Colorado children...
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