Article
Genetic susceptibility for autoimmune diseases and white blood cell count.
Scientific reports - 11 Apr 2023
Vaitinadin Nataraja Sarma, Stein C Michael, Mosley Jonathan D, Kawai Vivian K
Abstract excerpt
Some autoimmune (AI) conditions affect white blood cell (WBC) counts. Whether a genetic predisposition to AI disease associates with WBC counts in populations expected to have low numbers of AI cases is not known. We developed genetic instruments for 7 AI diseases using genome-wide association study summary statistics. Two-sample inverse variance weighted regression (IVWR) was used to determine associations...
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