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Article

Genetic variation and systemic lupus erythematosus: A field synopsis and systematic meta-analysis.

Autoimmunity reviews - 1 Jun 2018

Jeong Dong Yeon, Lee Sang Woo, Park Young Ha, Choi Ji Hoon, Kwon Young Wook, Moon Gabin, Eisenhut Michael, Kronbichler Andreas, Shin Jae Il

Abstract excerpt

Systemic lupus erythematosus (SLE) is a multi-systemic severe autoimmune disease which results from the irreversible loss of self-tolerance and impaired molecular responses, especially an altered interferon signature. We synthesized all meta-analyses reporting a genetic association of SLE, and further investigated their validity to discover false positive results under Bayesian methods. We executed a PubMed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29635078
DOI: 10.1016/j.autrev.2017.12.011

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