Article
Hematopoietic stem cells.
Birth defects research. Part C, Embryo today : reviews - 1 Aug 2003
Bonnet Dominique
Abstract excerpt
Considerable effort has been made in recent years in defining the embryonic origin of the hematopoietic stem cell (HSC). Using transgenic mouse models, a number of genes that regulate the formation, self-renewal, or differentiation of HSCs have been identified. Of particular interest, it has recently been shown that key regulators of definitive blood formation played a crucial role in adult HSC development....
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