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Stem Cells, Hematopoiesis and Lineage Tracing: Transplantation-Centric Views and Beyond

27 Apr 2022

Abstract excerpt

An appropriate production of mature blood cells, or hematopoiesis, is essential for organismal health and homeostasis. In this developmental cascade, hematopoietic stem cells (HSCs) differentiate into intermediate progenitor types, that subsequently give rise to the many distinct blood cell lineages. Here, we describe tools and methods that permit for temporal and native clonal-level HSC lineage tracing in the...

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PMID: 35573680
DOI: 10.3389/fcell.2022.903528

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