Article
Postnatal conservation of human blood- and marrow-specific CD34+ hematopoietic phenotypes.
Experimental hematology - 1 May 2022
Hammond Colin A, Eaves Connie J
Abstract excerpt
Previous studies of aging have revealed intrinsically determined alterations in the properties of the hematopoietic stem cell (HSC) and progenitor compartments in mice, with variable evidence of an extension of these findings to humans. To examine more closely the surface phenotypes within the CD34+ compartment of human blood and bone marrow from birth to old age, we undertook a 13-parameter phenotypic profile...
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