Article
Transient mutation bias increases the predictability of evolution on an empirical genotype-phenotype landscape.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 22 May 2023
Horton James S, Ali Shani U P, Taylor Tiffany B
Abstract excerpt
Predicting how a population will likely navigate a genotype-phenotype landscape requires consideration of selection in combination with mutation bias, which can skew the likelihood of following a particular trajectory. Strong and persistent directional selection can drive populations to ascend toward a peak. However, with a greater number of peaks and more routes to reach them, adaptation inevitably becomes less...
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