Reconstructing the genotype-to-fitness map for the bacterial chemotaxis network and its emergent behavioural phenotypes.

Abstract excerpt

The signal-transduction network responsible for chemotaxis in Escherichia coli has been characterised in extraordinary detail. Yet, relatively little is known about eco-evolutionary aspects of chemotaxis, such as how the network has been shaped by selection and to what extent natural populations may fine-tune their chemotactic behaviour to the ecological conditions. To address these questions, we here develop an...

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