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Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities

30 Mar 2023

Abstract excerpt

Pediatric solid and central nervous system tumors are the leading cause of cancer-related death among children. Identifying new targeted therapies necessitates the use of pediatric cancer models that faithfully recapitulate the patient's disease. However, the generation and characterization of pediatric cancer models has significantly lagged behind adult cancers, underscoring the urgent need to develop...

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PMID: 37001527
DOI: 10.1016/j.ccell.2023.03.007

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