MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research.

doi:10.1158/1078-0432.CCR-15-2717

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Article

MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2016

Chang Wendy, Brohl Andrew S, Patidar Rajesh, Sindiri Sivasish, Shern Jack F, Wei Jun S, Song Young K, Yohe Marielle E, Gryder Berkley, Zhang Shile, Calzone Kathleen A, Shivaprasad Nityashree, Wen Xinyu, Badgett Thomas C, Miettinen Markku, Hartman Kip R, League-Pascual James C, Trahair Toby N, Widemann Brigitte C, Merchant Melinda S, Kaplan Rosandra N, Lin Jimmy C, Khan Javed

Abstract excerpt

PURPOSE: We undertook a multidimensional clinical genomics study of children and adolescent young adults with relapsed and refractory cancers to determine the feasibility of genome-guided precision therapy. EXPERIMENTAL DESIGN: Patients with non-central nervous system solid tumors underwent a combination of whole exome sequencing (WES), whole transcriptome sequencing (WTS), and high-density single-nucleotide...

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Identifiers

PMID: 26994145
DOI: 10.1158/1078-0432.CCR-15-2717
PMCID: PMC4970946

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Source receipt: pubmed, retrieved 7 Sept 2026.

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