Article
Pathophysiology of MDS: genomic aberrations.
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2016
Ichikawa Motoshi
Abstract excerpt
Myelodysplastic syndromes (MDS) are characterized by clonal proliferation of hematopoietic stem/progenitor cells and their apoptosis, and show a propensity to progress to acute myelogenous leukemia (AML). Although MDS are recognized as neoplastic diseases caused by genomic aberrations of hematopoietic cells, the details of the genetic abnormalities underlying disease development have not as yet been fully...
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