Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic Switch and Growth of Melanoma Spheroids in the Presence of Mast Cells: Potential Impact of Nutrient-starvation Effects.

Anticancer research - 1 Apr 2023

Grujic Mirjana, Nguyen Thanh, Héchard Tifaine, Wang Helen, Lampinen Maria, Paivandy Aida, Pejler Gunnar

Abstract excerpt

BACKGROUND/AIM: Mast cells are abundant in melanoma tumors, and studies suggest that they can be either detrimental or protective for melanoma growth. However, the underlying mechanisms are not fully understood. MATERIALS AND METHODS: Here, we adopted an established hanging-drop spheroid system to investigate how mast cells influence melanoma growth and phenotype in a 3-D context. To address the underlying...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Culture Media, Conditioned
Share to Mast Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanoma

Share to Phenotype

Share to Spheroids, Cellular

Source

Identifiers

PMID: 36974825
DOI: 10.21873/anticanres.16290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic Switch and Growth of Melanoma Spheroids in the Presence of Mast Cells: Potential Impact of Nutrient-starvation Effects.PMID 36974825Read ↗

Heterotypic signaling between dermal fibroblasts and melanoma cells induces phenotypic plasticity and proteome rearrangement in malignant cells.Semantic proximity Read ↗

Different growth and metastatic phenotypes associated with a cell-intrinsic change of Met in metastatic melanoma.Semantic proximity Read ↗

Detachment stress mediated bioenergetic switch of malignant melanoma cells into anti-Warburg phenotype.Semantic proximity Read ↗

Fibroblasts Contribute to Melanoma Tumor Growth and Drug ResistanceSemantic proximity Read ↗

Melanin enhances metastatic melanoma colonization by inhibiting ferroptosisSemantic proximity Read ↗

Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins.Semantic proximity Read ↗

Detachment Stress Mediated Bioenergetic Switch of Malignant Melanoma Cells Into Anti-Warburg PhenotypeSemantic proximity Read ↗

Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain MetastasisSemantic proximity Read ↗

Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticitySemantic proximity Read ↗

Biophysical characterization of melanoma cell phenotype markers during metastatic progression.Semantic proximity Read ↗

Microfluidic model with air-walls reveals fibroblasts and keratinocytes modulate melanoma cell phenotype, migration, and metabolism.Semantic proximity Read ↗

Interactions of melanocytes and melanoma cells with the microenvironment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.