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Article

Different growth and metastatic phenotypes associated with a cell-intrinsic change of Met in metastatic melanoma.

Oncotarget - 25 Oct 2016

Adachi Eri, Sakai Katsuya, Nishiuchi Takumi, Imamura Ryu, Sato Hiroki, Matsumoto Kunio

Abstract excerpt

A dynamic phenotypic change contributes to the metastatic progression and drug resistance in malignant melanoma. Nevertheless, mechanisms for a phenotypic change have remained to be addressed. Here, we show that Met receptor expression changes in a cell-autonomous manner and can distinguish phenotypical differences in growth, as well as in metastatic and drug-resistant characteristics. In metastatic melanoma, the...

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Identifiers

PMID: 27683122
DOI: 10.18632/oncotarget.12221
PMCID: PMC5342589

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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