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Article

A Bayesian approach to incorporate structural data into the mapping of genotype to antigenic phenotype of influenza A(H3N2) viruses.

PLoS computational biology - 1 Mar 2023

Harvey William T, Davies Vinny, Daniels Rodney S, Whittaker Lynne, Gregory Victoria, Hay Alan J, Husmeier Dirk, McCauley John W, Reeve Richard

Abstract excerpt

Surface antigens of pathogens are commonly targeted by vaccine-elicited antibodies but antigenic variability, notably in RNA viruses such as influenza, HIV and SARS-CoV-2, pose challenges for control by vaccination. For example, influenza A(H3N2) entered the human population in 1968 causing a pandemic and has since been monitored, along with other seasonal influenza viruses, for the emergence of antigenic drift...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hemagglutinin Glycoproteins, Influenza Virus

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Source

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Identifiers

PMID: 36972311
DOI: 10.1371/journal.pcbi.1010885
PMCID: PMC10079231

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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