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Article

Prediction, dynamics, and visualization of antigenic phenotypes of seasonal influenza viruses.

Proceedings of the National Academy of Sciences of the United States of America - 22 Mar 2016

Neher Richard A, Bedford Trevor, Daniels Rodney S, Russell Colin A, Shraiman Boris I

Abstract excerpt

Human seasonal influenza viruses evolve rapidly, enabling the virus population to evade immunity and reinfect previously infected individuals. Antigenic properties are largely determined by the surface glycoprotein hemagglutinin (HA), and amino acid substitutions at exposed epitope sites in HA mediate loss of recognition by antibodies. Here, we show that antigenic differences measured through serological assay...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hemagglutinin Glycoproteins, Influenza Virus

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Source

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Identifiers

PMID: 26951657
DOI: 10.1073/pnas.1525578113
PMCID: PMC4812706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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