Article
Predicting the emergence of H3N2 influenza viruses reveals contrasted modes of evolution of HA and NA antigens.
Journal of molecular evolution - 1 Jan 2014
Sandie Reatha, Aris-Brosou Stéphane
Abstract excerpt
Vaccine design for rapidly changing viruses is based on empirical surveillance of strains circulating in a given season to assess those that will most likely spread during the next season. The choice of which strains to include in the vaccine is critical, as an erroneous decision can lead to a nonimmunized human population that will then be at risk in the face of an epidemic or, worse, a pandemic. Here, we...
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