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Article

Inference of genotype-phenotype relationships in the antigenic evolution of human influenza A (H3N2) viruses.

PLoS computational biology - 1 Jan 2012

Steinbrück Lars, McHardy Alice Carolyn

Abstract excerpt

Distinguishing mutations that determine an organism's phenotype from (near-) neutral 'hitchhikers' is a fundamental challenge in genome research, and is relevant for numerous medical and biotechnological applications. For human influenza viruses, recognizing changes in the antigenic phenotype and a strains' capability to evade pre-existing host immunity is important for the production of efficient vaccines. We...

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Share to Antigens, Viral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Influenza A Virus, H3N2 Subtype

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Identifiers

PMID: 22532796
DOI: 10.1371/journal.pcbi.1002492
PMCID: PMC3330098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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