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Article

Integrative analysis of individual-level data and high-dimensional summary statistics.

Bioinformatics (Oxford, England) - 3 Apr 2023

Fu Sheng, Deng Lu, Zhang Han, Qin Jing, Yu Kai

Abstract excerpt

MOTIVATION: Researchers usually conduct statistical analyses based on models built on raw data collected from individual participants (individual-level data). There is a growing interest in enhancing inference efficiency by incorporating aggregated summary information from other sources, such as summary statistics on genetic markers' marginal associations with a given trait generated from genome-wide association...

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PMID: 36964712
DOI: 10.1093/bioinformatics/btad156
PMCID: PMC10361352

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