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Article

Clinicopathologic Features of IDH2 R172-Mutated Myeloid Neoplasms.

American journal of clinical pathology - 5 Jul 2023

Davis Adam R, Canady Briana C, Aggarwal Nidhi, Bailey Nathanael G

Abstract excerpt

OBJECTIVES: IDH1 and IDH2 are among the most commonly mutated genes in myeloid neoplasms (MNs). It has been proposed that IDH2 R172 mutations (mR172) define a molecular subtype of acute myeloid leukemia (AML), but the clinicopathologic features of AML with mR172 have not been fully described. METHODS: We retrospectively identified and characterized all mR172 MNs with increased blasts in our archive for comparison...

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PMID: 36946516
DOI: 10.1093/ajcp/aqad019

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