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Article

Therapeutic potential of Clostridium butyricum anticancer effects in colorectal cancer

20 Mar 2023

Abstract excerpt

(C.B) are involved in regulating disease and cancers, yet the mechanistic basis for these regulatory roles remains largely unknown. Here, we demonstrate that C.B reprograms the proliferation, migration, stemness, and tumor growth in CRC by regulating pivotal signal molecules including MYC. Destabilization of MYC by C.B supplementation suppresses cancer cell proliferation/metastasis, sensitizes 5-FU treatment, and...

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Identifiers

PMID: 36941257
DOI: 10.1080/19490976.2023.2186114

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