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Pyrogallol Modulates Abscopal Tumour and Gut Microbial Responses to Localized Irradiation in an Ehrlich Ascites Carcinoma Model

2026-08-19

Abstract excerpt

Radiotherapy’s clinical utility is often limited by radio-resistance, enterotoxicity, and intestinal dysbiosis. This study evaluated pyrogallol—a plant-derived vicinal trihydroxybenzene—as a dual-action radiosensitizer and mucosal protectant in an Ehrlich ascites carcinoma (EAC) BALB/c mouse model subjected to targeted LINAC irradiation (8 Gy). By combining transcriptomic profiling with whole-genome metagenomic se...

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Literature Corpus work
6fdebdf6-00a7-5236-9a09-97d4484803a3
DOI
10.64898/2026.08.16.745132
Open publication

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Pyrogallol Modulates Abscopal Tumour and Gut Microbial Responses to Localized Irradiation in an Ehrlich Ascites Carcinoma ModelDOI 10.64898/2026.08.16.745132
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