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Article

Efficacy of Low-Dose Aspirin in Colorectal Cancer Risk Prevention is Dependent on ADH1B and ALDH2 Genotype in Japanese Familial Adenomatous Polyposis Patients.

Cancer research communications - 1 Jun 2022

Mure Kanae, Ishikawa Hideki, Mutoh Michihiro, Horinaka Mano, Otani Takahiro, Suzuki Sadao, Wakabayashi Keiji, Sakai Toshiyuki

Abstract excerpt

Aspirin has gained great attention as a cancer preventive agent. Our previous study revealed that the low-dose aspirin prevents colorectal tumor recurrence in Japanese patients with colorectal adenomas and/or adenocarcinomas, whereas aspirin increases risks in smokers and has no effects on regular drinkers. Our recent study revealed that aspirin reduces polyp growth in Japanese patients with familial adenomatous...

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Share to Adenomatous Polyposis Coli
Share to Aldehyde Dehydrogenase, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Colorectal Neoplasms

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Share to Neoplasm Recurrence, Local

Share to Polymorphism, Genetic

Source

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Identifiers

PMID: 36923554
DOI: 10.1158/2767-9764.CRC-22-0088
PMCID: PMC10010329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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