Article
Chemoprevention in familial adenomatous polyposis.
Best practice & research. Clinical gastroenterology - 1 Aug 2011
Kim Brian, Giardiello Francis M
Abstract excerpt
Familial adenomatous polyposis (FAP) predictably leads to adenomas and eventual adenocarcinomas in the lower gastrointestinal tract and less frequently, the upper gastrointestinal tract. Chemopreventive strategies have been studied in FAP patients to delay the development of adenomas in the upper and lower gastrointestinal tract, as well as to prevent recurrence of adenomas in the retained rectum of patients...
Topics
- Adenomatous Polyposis Coli
- Animals
- Anticarcinogenic Agents
- Chemoprevention
- Colectomy
- Colorectal Neoplasms
- Disease Progression
- Genetic Predisposition to Disease
- Humans
- Risk Assessment
- Risk Factors
- Treatment Outcome
