Article
Polygenic prediction of bipolar disorder in a Latin American sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2000
Cuellar-Barboza Alfredo B, Prieto Miguel L, Coombes Brandon J, Gardea-Resendez Manuel, Núñez Nicolás, Winham Stacey J, Romo-Nava Francisco, González Sarai, McElroy Susan L, Frye Mark A, Biernacka Joanna M
Abstract excerpt
To date, bipolar disorder (BD) genetic studies and polygenic risk scores (PRSs) for BD are based primarily on populations of European descent (EUR) and lack representation from other ancestries including Latin American (LAT). Here, we describe a new LAT cohort from the Mayo Clinic Bipolar Biobank (MCBB), a multisite collaboration with recruitment sites in the United States (EUR; 1,443 cases and 777 controls) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.