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Article

Genomic analysis of cervical carcinoma identifies Alpelisib as a therapeutic option for PIK3CA-mutant cervical carcinoma via the PI3K/AKT pathway.

Journal of medical virology - 1 Mar 2023

Wei Ye, Lin Shitong, Zhi Wenhua, Chu Tian, Liu Binghan, Peng Ting, Xu Miaochun, Ding Wencheng, Cao Canhui, Wu Peng

Abstract excerpt

Cervical carcinoma is a serious type of gynecological cancer that can affect women of all ages. Cervical carcinoma presents challenges for precision medicine, as not all tumors have specific gene mutations or alterations that can be targeted with existing drugs. Nonetheless, there are some promising targets in cervical carcinoma. Herein, genomic mutation data from The Cancer Genome Atlas and Catalogue of Somatic...

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Cancer Mechanisms and Therapy
Cisplatin
Class I Phosphatidylinositol 3-Kinases
Genomics
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phosphatidylinositol 3-Kinases

Proto-Oncogene Proteins c-akt

Uterine Cervical Neoplasms

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PMID: 36905114
DOI: 10.1002/jmv.28656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Genomic analysis of cervical carcinoma identifies Alpelisib as a therapeutic option for PIK3CA-mutant cervical carcinoma via the PI3K/AKT pathway.PMID 36905114Read ↗

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