Article
Autoimmune Regulator Gene Polymorphisms and the Risk of Primary Immune Thrombocytopenic Purpura: A Case-Control Study.
International journal of molecular sciences - 5 Mar 2023
Abdel Ghafar Muhammad T, Elshora Ola A, Allam Alzahraa A, Mashaal Raghda Gabr, Hamous Shereen Awny Abdelsalam, Abd El-Khalik Sarah Ragab, Abd-Ellatif Rania Nagi, Mariah Reham A, Eissa Radwa, Mwafy Mai, Shalaby Rasha E, Nasif Elham, Elkholy Rasha A
Abstract excerpt
This study aimed to assess the possible association between two single nucleotide polymorphisms (SNPs) of the autoimmune regulator (AIRE) gene (rs2075876 G/A and rs760426 A/G) with the risk of primary immune thrombocytopenia (ITP), as well as AIRE serum levels, in the Egyptian population. In this case-control study, 96 cases with primary ITP and 100 healthy subjects were included. Two SNPs of the AIRE gene...
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