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Association of autoimmune regulator gene polymorphism with susceptibility to rheumatoid arthritis in Egyptian population.

Immunologic research - 1 Apr 2020

A Moneim Nermeen Hassan, Mansour Mona Farouk, Omar Hanan Hassan, Fouad Marwa Mohamed, Metwally Lobna, El-Abaseri Taghrid B, Abdelnaby Mai Mohamed

Abstract excerpt

The autoimmune regulator (AIRE) gene controls autoimmunity via its transcript AIRE protein that suppresses naïve T cells during central selection. The role of AIRE polymorphism in rheumatoid arthritis (RA) autoimmunity remains elusive. This study aimed to investigate the association of two selected SNPs, namely, rs760426 and rs2075876, with RA susceptibility in the Suez Canal Zone population. The study population...

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PMID: 32399858
DOI: 10.1007/s12026-020-09127-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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