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Article

Association of rs2075876 polymorphism of AIRE gene with rheumatoid arthritis risk.

Human immunology - 1 Apr 2015

Feng Zhong-Jun, Zhang Shu-Lan, Wen Hai-Feng, Liang Yun

Abstract excerpt

BACKGROUND: Autoimmune regulator (AIRE), a protein encoded by AIRE gene, is a transcriptional factor primarily expressed in medullary thymic epithelial cells (mTECs). It has pivotal role in regulation of human immunology. The mutations of AIRE gene or protein level changes would alter the status of body immunity and therefore onset of diseases. Therefore we aimed at investigating the association of AIRE gene with...

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PMID: 25637666
DOI: 10.1016/j.humimm.2015.01.026

Genes

AIRE
CRP

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