Article
MutationalPatterns: the one stop shop for the analysis of mutational processes.
BMC genomics - 15 Feb 2022
Manders Freek, Brandsma Arianne M, de Kanter Jurrian, Verheul Mark, Oka Rurika, van Roosmalen Markus J, van der Roest Bastiaan, van Hoeck Arne, Cuppen Edwin, van Boxtel Ruben
Abstract excerpt
BACKGROUND: The collective of somatic mutations in a genome represents a record of mutational processes that have been operative in a cell. These processes can be investigated by extracting relevant mutational patterns from sequencing data. RESULTS: Here, we present the next version of MutationalPatterns, an R/Bioconductor package, which allows in-depth mutational analysis of catalogues of single and double base...
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