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Article

All-Natural Immunomodulatory Bioadhesive Hydrogel Promotes Angiogenesis and Diabetic Wound Healing by Regulating Macrophage Heterogeneity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) - 1 May 2023

Fu Ya-Jun, Shi Yi-Feng, Wang Li-Ya, Zhao Yi-Fan, Wang Rao-Kaijuan, Li Kai, Zhang Shu-Ting, Zha Xiang-Jun, Wang Wei, Zhao Xing, Yang Wei

Abstract excerpt

Macrophages are highly heterogeneous and exhibit a diversity of functions and phenotypes. They can be divided into pro-inflammatory macrophages (M1) and anti-inflammatory macrophages (M2). Diabetic wounds are characterized by a prolonged inflammatory phase and difficulty in healing due to the accumulation of pro-inflammatory (M1) macrophages in the wound. Therefore, hydrogel dressings with macrophage...

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Identifiers

PMID: 36862027
DOI: 10.1002/advs.202206771
PMCID: PMC10161050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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