Article
Modulating macrophage phenotype for accelerated wound healing with chlorogenic acid-loaded nanocomposite hydrogel.
Journal of controlled release : official journal of the Controlled Release Society - 1 May 2024
Wang Shuangqing, Liu Yanhong, Wang Xusheng, Chen Liqing, Huang Wei, Xiong Tianning, Wang Nuoya, Guo Jianpeng, Gao Zhonggao, Jin Mingji
Abstract excerpt
Wound healing involves distinct phases, including hemostasis, inflammation, proliferation, and remodeling, which is a complex and dynamic process. Conventional preparations often fail to meet multiple demands and provide prompt information about wound status. Here, a pH/ROS dual-responsive hydrogel (OHA-PP@Z-CA@EGF) was constructed based on oxidized hyaluronic acid (OHA), phenylboronic acid-grafted ε-polylysine...
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