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Article

Interpenetrating gallol functionalized tissue adhesive hyaluronic acid hydrogel polarizes macrophages to an immunosuppressive phenotype.

Acta biomaterialia - 1 Apr 2022

Samanta Sumanta, Rangasami Vignesh K, Sarlus Heela, Samal Jay R K, Evans Austin D, Parihar Vijay S, Varghese Oommen P, Harris Robert A, Oommen Oommen P

Abstract excerpt

Innovative scaffold designs that modulate the local inflammatory microenvironment through favorable macrophage polarization and suppressing oxidative stress are needed for successful clinical translation of regenerative cell therapies and graft integration. We herein report derivation of a hydrazone-crosslinked gallol functionalized hyaluronic acid (HA-GA)-based hydrogel that displayed outstanding viscoelastic...

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Identifiers

PMID: 35085799
DOI: 10.1016/j.actbio.2022.01.048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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