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Therapeutic potential of CDK11 in cancer

28 Feb 2023

Abstract excerpt

Human cyclin-dependent kinases (CDKs) direct the progression of the cell cycle and transcription. They are deregulated in tumours, and despite their involvement in the regulation of basic cellular processes, many CDKs are promising targets for cancer therapy. CDK11 is an essential gene for the growth of many malignancies; however, its primary cellular function has been obscure, and the mode-of-action of OTS964,...

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PMID: 36855776
DOI: 10.1002/ctm2.1201

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