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Article

CDK9: A key player in cancer and other diseases

19 Jul 2017

Abstract excerpt

Cyclin-Dependent Kinase 9 (CDK9) is part of a functional diverse group of enzymes responsible for cell cycle control and progression. It associates mainly with Cyclin T1 and forms the Positive Transcription Elongation Factor b (p-TEFb) complex responsible for regulation of transcription elongation and mRNA maturation. Recent studies have highlighted the importance of CDK9 in many relevant pathologic processes,...

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PMID: 28722178
DOI: 10.1002/jcb.26293

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