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Article

SARS-CoV-2 Nsp2 Contributes to Inflammation by Activating NF-κB

24 Jan 2023

Abstract excerpt

COVID-19 is associated with robust inflammation and partially impaired antiviral responses. The modulation of inflammatory gene expression by SARS-CoV-2 is not completely understood. In this study, we characterized the inflammatory and antiviral responses mounted during SARS-CoV-2 infection. K18-hACE2 mice were infected with a Wuhan-like strain of SARS-CoV-2, and the transcriptional and translational expression...

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PMID: 36851549
DOI: 10.3390/v15020334

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