Article

SARS-CoV-2 Nsp2 reprograms host immunity to drive pathogenic inflammation

2026-05-07

Abstract excerpt

Despite the end of the COVID-19 pandemic, SARS-CoV-2 continues to circulate endemically, highlighting the need to better understand the viral determinants of pathogenesis. Non-structural protein 2 (Nsp2) has been implicated in host–virus interactions, yet its function remains poorly defined in the context of infection. Here, we generated a recombinant SARS-CoV-2 lacking Nsp2 (ΔNsp2) to investigate its role in vira...

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Literature Corpus work: a7cc1fc6-47cd-56e3-ba40-be10ca2251ff
DOI: 10.64898/2026.05.06.723222

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