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Article

Expanding the Spectrum of BRAF Non-V600E Mutations in Thyroid Nodules: Evidence-Based Data from a Tertiary Referral Centre.

International journal of molecular sciences - 17 Feb 2023

De Leo Antonio, Serban Daniela, Maloberti Thais, Sanza Viviana, Coluccelli Sara, Altimari Annalisa, Gruppioni Elisa, Chiarucci Federico, Corradini Angelo Gianluca, Repaci Andrea, Colapinto Alessandra, Nannini Margherita, Pantaleo Maria A, de Biase Dario, Tallini Giovanni

Abstract excerpt

The BRAF p.V600E mutation represents the most specific marker for papillary thyroid carcinoma and is potentially related to aggressive behavior and persistent disease. BRAF alterations other than the p.V600E are less common in thyroid carcinoma and represent an alternative mechanism of BRAF activation with unclear clinical significance. The study aims to describe the frequency and clinicopathologic...

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Share to Adenocarcinoma, Follicular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Share to Thyroid Cancer, Papillary

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Source

Open in PubMed Open full text

Identifiers

PMID: 36835466
DOI: 10.3390/ijms24044057
PMCID: PMC9958561

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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