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Article

Reappraisal of BRAFK601E-positive thyroid tumors in the NIFTP era.

Endocrine-related cancer - 1 Dec 2024

Doerfler William R, Nikitski Alyaksandr V, Keating Shannon, Spagnolo Daniel, Kaya Cihan, Morariu Elena M, Karslioglu French Esra, Yip Linwah, Nikiforova Marina N, Wald Abigail I, Nikiforov Yuri E

Abstract excerpt

BRAFK601E is an uncommon mutation typically found in encapsulated follicular-patterned thyroid tumors. Previous studies on BRAFK601E-positive thyroid tumors were conducted before the implementation of the non-invasive follicular neoplasm with papillary-like nuclear features (NIFTP) diagnosis. This study aimed to characterize BRAFK601E-positive tumors and evaluate changes in the diagnosis and management of these...

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Share to Mutation
Share to Adenocarcinoma, Follicular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRAF gene

Share to Neoplasm Recurrence, Local

Share to Proto-Oncogene Proteins B-raf

Share to Thyroid Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 39404355
DOI: 10.1530/ERC-24-0207
PMCID: PMC11703548

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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