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Article

Histopathologic and Clinical Characterization of Thyroid Tumors Carrying the BRAF(K601E) Mutation.

Thyroid : official journal of the American Thyroid Association - 1 Feb 2016

Afkhami Michelle, Karunamurthy Arivarasan, Chiosea Simion, Nikiforova Marina N, Seethala Raja, Nikiforov Yuri E, Coyne Christopher

Abstract excerpt

BACKGROUND: While the association of the BRAF(V600E) mutation with aggressive histopathological tumor features and clinical behavior has been extensively studied in papillary thyroid carcinoma (PTC), the BRAF(K601E) mutation has not been well characterized. This study reports what is currently the largest series of BRAF(K601E) mutated thyroid nodules. METHODS: Histopathologic, cytologic, and molecular reports...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26422023
DOI: 10.1089/thy.2015.0227

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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