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Article

Mendelian Randomization Study on Causal Association of IL-6With Breast Cancer.

Clinical breast cancer - 1 Jun 2023

Zhang Min, Ma Ning, Wang Renxi

Abstract excerpt

BACKGROUND: Previous studies have shown an important role of interleukin 6 (IL-6) in the progression and metastasis of breast cancer. The present 2-sample Mendelian randomization (MR) study aimed to identify the genetic causal link between IL-6 and breast cancer. MATERIAL AND METHODS: IL-6-signaling and its negative regulator soluble IL-6 receptor (sIL-6R) genetic instruments were chosen from 2 large-scale...

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PMID: 36813657
DOI: 10.1016/j.clbc.2023.01.015

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