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Article

Circulating interleukin-6 and cancer: A meta-analysis using Mendelian randomization.

Scientific reports - 22 Jun 2015

Tian Geng, Mi Jia, Wei Xiaodan, Zhao Dongmei, Qiao Lingyan, Yang Chunhua, Li Xianglin, Zhang Shuping, Li Xuri, Wang Bin

Abstract excerpt

Interleukin-6 (IL-6) plays a contributory role in the progression and severity of many forms of cancer; it however remains unclear whether the relevance between circulating IL-6 and cancer is causal. We therefore meta-analyzed published articles in this regard using IL-6 gene -174G/C variant as an instrument. Seventy-eight and six articles were eligible for the association of -174G/C variant with cancer and...

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Identifiers

PMID: 26096712
DOI: 10.1038/srep11394
PMCID: PMC4476043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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